H21 Acne treatments through the ages
نویسندگان
چکیده
Abstract The search for an effective treatment acne dates back to 1550 Bc with the Ebers Papyrus, one of oldest medical documents in world, mentioning application raw honey and sulfur affected areas. King Tutankhamun is widely believed have suffered from as his tomb was filled popular treatments time such sulfur, sour milk, Aloe vera, myrrh salt rid him affliction afterlife. Much like Egyptians, ancient Greek texts mention acne. A physician named Theodosius suggested that patients wipe their spots a towel while watching star falling sky he this would result faces. Romans, addition aforementioned trialled crocodile meat, cypress oil, cheese, leek leaves cinnamon attempts find successful treatment. Thomas Bateman wrote Practical Synopsis Cutaneous Disease patient reported bruised parsley cleared her He also advocate remedies used by civilizations. At turn 20th century, American W.A. Pusay about use ionizing radiation Radiation until 1960s, when concerns regarding associated secondary carcinogenesis led out favour. In first half phototherapy acne, quartz mercury vapour lamps, particular, were used. most significant advancement discovery utility synthetic vitamin A. pharmaceutical company Roche compound 13-cis-retinoic acid skin cancer. This ineffective, but it demonstrated efficacious study published 1979 New England Journal Medicine 13 14 conglobate experienced clearance 1982, US Food Drug Administration granted approval acid, or isotretinoin, It introduced Europe 1983. Isotretinoin has been life-changing advance disease, its teratogenic effects mean must be prescribed education care.
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ژورنال
عنوان ژورنال: British Journal of Dermatology
سال: 2023
ISSN: ['1365-2133', '0007-0963']
DOI: https://doi.org/10.1093/bjd/ljad113.303